Product ID:SORBITRATE TABLETS
MSDS Date:05/20/1987
FSC:6505
NIIN:00-368-5751
MSDS Number: BHPFQ

Emergency Phone: 800-327-8633 MEDICAL

Info Phone: 302-886-3000

Cage: 13992

Telephone: 302-886-3000

Cage: 13992

ISOSORBIDE DINITRATE MIXTURE

CAS: 87-33-2

RTECS: LZ4386000

OTHER INGREDIENTS (MANUFACTURER STATES INGREDIENTS NOT

LD50 LC50 Mixture:LD50 (ORAL RAT) IS 945 MG/KG
Routes of Entry: Inhalation:NO Skin:NO Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ISOSORBIDE DINITRATE IS A
METHEMOGLOBIN FORMER, AND MAY CAUSE GASTROINTESTINAL DISTURBANCES
AND CENTRAL NERVOUS SYSTEM DEPRESSION. A SINGLE DOSE OF THIS
PRODUCT IS SLIGHTLY TOXIC BY INGESTION. THE LIF E-THREATENING DOSE
IN MAN IS PROBABLY AROUND 2.5 G/KG.
Explanation of Carcinogenicity:NONE OF THE CHEMICALS IN THIS PRODUCT IS
LISTED BY IARC, NTP OR OSHA AS A CARCINOGEN.
Effects of Overexposure:EYES:NO IRRITATION LIKELY TO DEVELOP. SKIN:NO
IRRITATION LIKELY TO DEVELOP. INHALATION:TABLETS ARE NOT LIKELY TO
BE INHALED, BUT ANY DUST CAN BE SLOWLY ABSORBED THROUGH MUCOUS
MEMBRANES.
Medical Cond Aggravated by Exposure:NONE NOTED.

First Aid:EYES:IMMEDIATELY FLUSH WITH PLENTY OF WATER FOR AT LEAST 15
MINUTES.SEE DOCTOR. SKIN:WASH WITH SOAP AND WATER.
INHALATION:REMOVE TO FRESH AIR.GIVE OXYGEN/CPR IF NEEDED.SEE
DOCTOR. INGESTION:GIVE 1 OR 2 GLASSES OF WATER.INDUCE VOMIT.SEE
DOCTOR. NOTE TO PHYSICIAN:SEVERE OVEREXPOSURE CAN, IN THEORY, LEAD
TO METHEMOGLOBIN FORMATION, WHICH IN SUFFICIENT CONCENTRATIONS
RESULTS IN CLINICAL CYANOSIS.

Extinguishing Media:USE WATER FOG, CARBON DIOXIDE, FOAM, OR DRY
CHEMICAL.
Fire Fighting Procedures:FIRE FIGHTERS SHOULD USE NIOSH APPROVED SCBA &
FULL PROTECTIVE EQUIPMENT WHEN FIGHTING CHEMICAL FIRE. USE WATER
SPRAY TO COOL NEARBY CONTAINERS EXPOSED TO FIRE.
Unusual Fire/Explosion Hazard:CONCENTRATED ISOSORBIDE IS A POWERFUL
EXPLOSIVE.ANY SEPARATION OF IT FROM OTHER INGREDIENTS IN THE
MIXTURE,EVEN IN SMALL AMOUNTS IS EXTREMELY HAZARDOUS.

Spill Release Procedures:WEAR SKIN PROTECTION DURING CLEANUP. SWEEP UP
AND RECOVER. WET MATERIAL WITH WATER IN A PLASTIC BAG OR PLASTIC
LINED CONTAINER. WHEN TABLETS BEGIN TO DISINTEGRATE, DISCARD WITH
GENERAL TRASH. FLUSH RE SIDUE WITH LARGE AMOUNTS OF WATER.
Neutralizing Agent:NONE APPLICABLE FOR THIS MATERIAL

Handling and Storage Precautions:STORE IN COOL, DRY, WELL VENTILATED
AREA. PROTECT FROM PHYSICAL DAMAGE, HEAT AND IGNITION SOURCES. KEEP
CONTAINERS CLOSED.
Other Precautions:AVOID BREATHING DUST. PREVENT SKIN CONTACT.

Respiratory Protection:NONE NORMALLY REQUIRED.
Ventilation:NORMAL ROOM VENTILATION.
Protective Gloves:COTTON GLOVES OVER THIN LATEX GLOVES.
Eye Protection:SAFETY GLASSES WITH SIDE SHIELD.
Other Protective Equipment:NONE NORMALLY REQUIRED.
Work Hygienic Practices:WASH THROUGHLY AFTER HANDLING AND BEFORE
EATING.
Supplemental Safety and Health
NONE.

HCC:N1
Melt/Freeze Pt:M.P/F.P Text:158F,70C
Solubility in Water:SLIGHT
Appearance and Odor:TABLETS
Percent Volatiles by Volume:NEGL.

Stability Indicator/Materials to Avoid:YES
WATER, ACIDS, ALKALIES, OXIDIZING AGENTS.
Stability Condition to Avoid:HEAT, PERCUSSION.
Hazardous Decomposition Products:CARBON DIOXIDE, CARBON MONOXIDE,
NITROGEN OXIDES.

Waste Disposal Methods:DISPOSE OF IN ACCORDANCE WITH ALL APPLICABLE
FEDERAL, STATE AND LOCAL LAWS AND REGULATIONS. DISCARDED PRODUCT IS
NOT A HAZARDOUS WASTE UNDER RCRA. EMPTY CONTAINERS CONTAINS
RESIDUE, DO NOT REUSE.DESTR OY EMPTY CONTAINER BEFORE DISPOSAL.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.